The fact that H. pylori lives quietly inside the human stomach is what makes it such a successful organism. In most people there are no symptoms of infection,while in others the symptoms are mild.Only a tiny percentage exhibit symptoms noticeable enough that the person seeks medical care, and this often occurs decades after the initial infection, leaving plenty of time to infect others along the way. Typically, the symptom that brings patients to the doctor is an intense ,gnawing or burning pain in the stomach, which signals the formation of an ulcer. Ulcers were once thought to be caused by emotional stress and lifestyle (alcohol, smoking, etc.), but it is now recognized that the majority of them are the result of H. pylori infection.
H. pylori infects over half the world’s population,but only about 10 percent ofthe population develop ulcers.This discrepancy has puzzled investigators for decades. Why do only certain people exhibit infection of h pylori symptoms ? Is it some property of the individual, or something about the organism that makes the disease worse in some individuals than others? The answer is probably both. Individual differences in how the host’s immune system responds to infection combined with the nature of the infecting strain (i.e.,what genes it carries) conspire to create greater damage in some people than in others.The diseases that H.pylori causes are thought to arise as a result of both direct damage by the bacterium and injury brought about by the host’s own immune system.
Other infection symptoms may be associated with H. pylori
An ache or burning pain in your abdomen
Abdominal pain that’s worse when your stomach is empty
Loss of appetite
Unintentional weight loss