Sarah Silverman Archive

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Jaundice

Jaundice is the abnormal accumulation of bilirubin in body tissues which occurs when the serum bilirubin level exceeds 50 µmol/L (3 mg/dL). Excess bilirubin causes a yellow tinting to the skin, sclera and mucous membranes. A basic knowledge of bilirubin metabolism is necessary to understand the investigations

Crohn Disease and Ulcerative Colitis

Crohn disease and ulcerative colitis are inflammatory bowel diseases (IBDs) of undetermined cause. The diseases strike rich and poor, men and women, whites, blacks, and Asians. It is most frequently diagnosed in individuals between fifteen and thirty years of age. The Crohn’s & Colitis Foundation of America

Peptic Ulcer Symptoms and Signs

Peptic ulcer is a break in the gastric or duodenal mucosa that arises when the normal mucosal defensive factors are impaired or are overwhelmed by aggressive luminal factors such as acid and pepsin. By definition, ulcers extend through the muscularis mucosae and are usually over 5 mm

Helicobacter pylori Gastritis

H pylori is a spiral gram-negative rod that resides beneath the gastric mucous layer adjacent to gastric epithelial cells. Although not invasive, it causes gastric mucosal inflammation with PMNs and lymphocytes. The mechanisms of injury and inflammation may in part be related to the products of two

Indigestion Symptoms and Signs , Treatment

▶ Symptoms and Signs The discomfort may be characterized by one or more upper abdominal symptoms including epigastric pain or burning, early satiety, postprandial fullness, bloating, nausea, or vomiting. Concomitant weight loss, persistent vomiting, constant or severe pain, dysphagia, hematemesis, or melena warrants endoscopy or abdominal imaging. Potentially

Functional Dyspepsia Treatment

Functional Dyspepsia Functional Dyspepsia causes pain and sometimes other symptoms in your upper tummy (abdomen). The cause is often not clear. Medication to reduce stomach acid helps in some cases. Infection with Helicobacter pylori may cause a small number of cases. Clearing this infection, if present, helps in